好书推荐:Annual Reports in Medicinal Chemistry, Volume 43

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Annual Reports in Medicinal Chemistry, Volume 43By John E. Macor-----
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Publisher: Academic Press
Number Of Pages: 584
Publication Date: 2008-11-03
ISBN-10 / ASIN: 0123743443
ISBN-13 / EAN: 9780123743442
Binding: Paperback
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Product Description: Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. * covers findings related to cardiovascular, inflammation, and pulmonary diseases* examines issues in oncology, from mTor inhibitors to drug targets* incorporates up-to-date information on drug design and discovery, including delivery to marketPart I: Central Nervous System Diseases
5.
Chapter 1 Recent Advances in Corticotropin-Releasing Factor Receptor Antagonists
Pages 3-23
Carolyn D. Dzierba, Richard A. Hartz, Joanne J. Bronson
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6.
Chapter 2 Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors
Pages 25-42
Brock T. Shireman, Pascal Bonaventure, Nicholas I. Carruthers
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7.
Chapter 3 Recent Advances in Voltage-Gated Sodium Channel Blockers: Therapeutic Potential as Drug Targets in the CNS
Pages 43-60
Andreas Termin, Esther Martinborough, Dean Wilson
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8.
Chapter 4 Medication Development for the Treatment of Substance Abuse
Pages 61-72
Brian S. Fulton
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9.
Chapter 5 GPR40 (FFAR1) Modulators
Pages 75-85
Julio C. Medina, Jonathan B. Houze
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10.
Chapter 6 Rho-Kinase Inhibitors for Cardiovascular Disease
Pages 87-102
Robert A. Stavenger
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11.
Chapter 7 LXR Agonists for the Treatment of Atherosclerosis: Recent Highlights
Pages 103-117, 565-566
Jonathan Bennett, Andrew Cooke, Heather J. McKinnon, Olaf Nimz
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12.
Chapter 8 Glucagon Receptor Antagonists for Type II Diabetes
Pages 119-137
Duane E. DeMong, Michael W. Miller, Jean E. Lachowicz
Preview Related Articles Part III: Inflammation/Pulmonary/GI
13.
Chapter 9 Advances Toward Dissociated Non-Steroidal Glucocorticoid Receptor Agonists
Pages 141-154
John Regan, Hossein Razavi, David Thomson
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14.
Chapter 10 Advances in the Discovery of IκB Kinase Inhibitors
Pages 155-170
William J. Pitts, James Kempson
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15.
Chapter 11 Protease Inhibitors for the Potential Treatment of Chronic Obstructive Pulmonary Disease and Asthma
Pages 171-185
Weimin Liu, Eugene R. Hickey
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16.
Chapter 12 mTOR Inhibitors in Oncology
Pages 189-202
Jeroen Verheijen, Ker Yu, Arie Zask
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17.
Chapter 13 Oncology Drug Targets in the Sphingomyelin-Signaling Pathway
Pages 203-226
William Garland, Amy Cavalli, Geneviève Hansen
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18.
Chapter 14 Inhibitors of Respiratory Syncytial Virus
Pages 229-245, 567-569
Malcolm Carter, G. Stuart Cockerill
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19.
Chapter 15 Recent Developments in β-Lactamases and Inhibitors
Pages 247-267
Tarek S. Mansour, Patricia A. Bradford, Aranapakam M. Venkatesan
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20.
Chapter 16 Recent Development in the Treatment of Clostridium difficile Associated Disease (CDAD)
Pages 269-279
Xicheng Sun, Joseph Guiles, Nebojsa Janjic
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21.
Chapter 17 Recent Advances in the Discovery of Hybrid Antibacterial Agents
Pages 281-290
Michael R. Barbachyn
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22.
Chapter 18 Recent Renaissance of Prostaglandin Research
Pages 293-309
Robert M. Burk
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23.
Chapter 19 Human Exposure and Dose Projections
Pages 311-328
Punit H. Marathe, Christine Huang, A. David Rodrigues
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24.
Chapter 20 Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology Approach
Pages 329-349
Zoltán Sarnyai, László G. Boros
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25.
Chapter 21 Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence Absorption
Pages 353-371
John M. DeSesso, Amy Lavin Williams
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26.
Chapter 22 The Emerging Utility of Co-Crystals in Drug Discovery and Development
Pages 373-404
Nicholas A. Meanwell
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27.
Chapter 23 Pregnane X Receptor: Prediction and Attenuation of Human CYP3A4 Enzyme Induction and Drug–Drug Interactions
Pages 405-418
Michael W. Sinz
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28.
Chapter 24 Formulation in Drug Discovery
Pages 419-451
Robert G. Strickley
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29.
Chapter 25 To Market, To Market — 2007
Pages 455-497
Shridhar Hegde, Michelle Schmidt
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30.
Compound Name, Code Number and Subject Index, Volume 43
Pages 499-504
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